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Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

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4,000+ records

Systematic review / meta-analysis 2019
General medicine and research

Service user, carer and provider perspectives on integrated care for older people with frailty, and factors perceived to facilitate and hinder implementation: A systematic review and narrative synthesis.

PloS one

Introduction Older people with frailty (OPF) can experience reduced quality of care and adverse outcomes due to poorly coordinated and fragmented care, making this patient population a key target group for integrated care. This systematic review explores servi

Systematic review / meta-analysis 2021
Prevention and public health

The impact of methamphetamine/amphetamine use on receipt and outcomes of medications for opioid use disorder: a systematic review.

Addiction science & clinical practice

Background Methamphetamine/amphetamine use has sharply increased among people with opioid use disorder (OUD). It is therefore important to understand whether and how use of these substances may impact receipt of, and outcomes associated with, medications for O

Systematic review / meta-analysis 2019
Infections and immunity

The risk of systemic lupus erythematosus associated with Epstein-Barr virus infection: a systematic review and meta-analysis.

Clinical and experimental medicine

Previous systematic reviews have found a higher sero-prevalence of EBV antibodies in SLE patients compared with controls. Because many studies have been published, there is a need to apply more precise systematic review methods. We examined the association bet

Systematic review / meta-analysis 2022
General medicine and research

The role of keratinized mucosa width as a risk factor for peri-implant disease: A systematic review, meta-analysis, and trial sequential analysis.

Clinical implant dentistry and related research

Background Studies have examined the benefit of having keratinized peri-implant mucosa width with mixed results. Purpose This study examines whether the lack of a prespecified (2 mm) amount of keratinized mucosa width (KMW) is a risk factor for peri-implant di

Systematic review / meta-analysis 2020
General medicine and research

The Role of Selenium Mineral Trace Element in Exercise: Antioxidant Defense System, Muscle Performance, Hormone Response, and Athletic Performance. A Systematic Review.

Nutrients

Exercise overproduces oxygen reactive species (ROS) and eventually exceeds the body's antioxidant capacity to neutralize them. The ROS produce damaging effects on the cell membrane and contribute to skeletal muscle damage. Selenium (Se), a natural mineral trac

Systematic review / meta-analysis 2019
Lungs and breathing

Use of pedometers as a tool to promote daily physical activity levels in patients with COPD: a systematic review and meta-analysis.

European respiratory review : an official journal of the European Respiratory Society

The aim of this study was to examine the use of pedometers as a tool to promote daily physical activity levels in patients with COPD.A systematic review meta-analysis of pedometer physical activity promotion in patients with COPD was conducted. Medline/PubMed,

Systematic review / meta-analysis 2021
General medicine and research

Warfarin dosing algorithms: A systematic review.

British journal of clinical pharmacology

Aims Numerous algorithms have been developed to guide warfarin dosing and improve clinical outcomes. We reviewed the algorithms available for various populations and the covariates, performances and risk of bias of these algorithms. Methods We systematically s

Systematic review / meta-analysis 2021
General medicine and research

A systematic review and meta-analysis of technical aspects and clinical outcomes of botulinum toxin prior to abdominal wall reconstruction.

Hernia : the journal of hernias and abdominal wall surgery

Purpose To systematically review technical aspects and treatment regimens of botulinum toxin A (BTA) injections in the lateral abdominal wall musculature. We also investigated the effect of BTA on abdominal muscle- and hernia dimensions, and clinical outcome.

Systematic review / meta-analysis 2020
Prevention and public health

A systematic review on the role of microbiota in the pathogenesis and treatment of eating disorders.

European psychiatry : the journal of the Association of European Psychiatrists

Background There is growing interest in new factors contributing to the genesis of eating disorders (EDs). Research recently focused on the study of microbiota. Dysbiosis, associated with a specific genetic susceptibility, may contribute to the development of

Systematic review / meta-analysis 2021
Cancer and oncology

A Systematic Review on the Therapeutic Potentiality of PD-L1-Inhibiting MicroRNAs for Triple-Negative Breast Cancer: Toward Single-Cell Sequencing-Guided Biomimetic Delivery.

Genes

The programmed death-ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) is a well-established inhibitory immune checkpoint axis in triple-negative breast cancer (TNBC). Growing evidence indicates that tumoral PD-L1 can lead to TNBC development. Although c

Systematic review / meta-analysis 2019
Diabetes and metabolism

Burden, risk factors and maternal and offspring outcomes of gestational diabetes mellitus (GDM) in sub-Saharan Africa (SSA): a systematic review and meta-analysis.

BMC pregnancy and childbirth

Background The burden, determinants and outcomes of gestational diabetes mellitus (GDM) in sub-Saharan Africa are not known. We summarized existing evidence on the prevalence, risk factors and complications of GDM in the region. Methods PubMed was searched fro

Systematic review / meta-analysis 2020
General medicine and research

Can metacognitive interventions improve insight in schizophrenia spectrum disorders? A systematic review and meta-analysis.

Psychological medicine

Background Patients with schizophrenia spectrum disorders (SSD) tend to lack insight, which is linked to poor outcomes. The effect size of previous treatments on insight changes in SSD has been small. Metacognitive interventions may improve insight in SSD, alt

Systematic review / meta-analysis 2020
Cancer and oncology

Comparing hypofractionated to conventional fractionated radiotherapy in postmastectomy breast cancer: a meta-analysis and systematic review.

Radiation oncology (London, England)

Purpose To compare the efficacy and toxicity of hypofractionated radiotherapy versus conventional fractionated radiotherapy in postmastectomy breast cancer using meta-analysis. Methods The PubMed, EMbase, Cochrane Library, Google Scholar, Wan Fang and CNKI dat

Systematic review / meta-analysis 2018
General medicine and research

Contemporary global perspectives of medical students on research during undergraduate medical education: a systematic literature review.

Medical education online

Background The need for increased expertise in evidence-based medicine and concerns about the decreasing numbers of physician-scientists have underscored the need for promoting and encouraging research in medical education. The critical shortage of physician-s