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Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

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4,011+ records

Systematic review / meta-analysis 2022
Cancer and oncology

Endometrial hyperplasia as a risk factor of endometrial cancer.

Archives of gynecology and obstetrics

Endometrial hyperplasia (EH) is the precursor lesion for endometrioid adenocarcinoma of the endometrium (EC), which represents the most common malignancy of the female reproductive tract in industrialized countries. The most important risk factor for the devel…

Systematic review / meta-analysis 2021
Children's health

Environmental Risk Factors and Health: An Umbrella Review of Meta-Analyses.

International journal of environmental research and public health

Background : Environmental health is a growing area of knowledge, continually increasing and updating the body of evidence linking the environment to human health. Aim : This study summarizes the epidemiological evidence on environmental risk factors from meta…

Systematic review / meta-analysis 2020
General medicine and research

Pain level between clear aligners and fixed appliances: a systematic review.

Progress in orthodontics

Objectives To assess if there is any difference in pain levels between orthodontic treatment with clear aligners or fixed appliances. Materials and methods An electronic search was completed in PubMed, The Cochrane Database, Web of Science, Scopus, Lilacs, Goo…

Systematic review / meta-analysis 2020
General medicine and research

Shared and distinct functional networks for empathy and pain processing: a systematic review and meta-analysis of fMRI studies.

Social cognitive and affective neuroscience

Background Empathy for pain is a complex phenomenon incorporating sensory, cognitive and affective processes. Functional neuroimaging studies indicate a rich network of brain activations for empathic processing. However, previous research focused on core activ…

Systematic review / meta-analysis 2021
Cancer and oncology

The prognostic impact of tumor mutational burden (TMB) in the first-line management of advanced non-oncogene addicted non-small-cell lung cancer (NSCLC): a systematic review and meta-analysis of randomized controlled trials.

ESMO open

Background The role of tumor mutational burden (TMB) is still debated for selecting advanced non-oncogene addicted non-small-cell lung cancer (NSCLC) patients who might benefit from immune checkpoint inhibitors (ICIs). Of note, TMB failed to predict a benefit …

Systematic review / meta-analysis 2019
Prevention and public health

Effectiveness of Interventions and Behaviour Change Techniques for Improving Dietary Intake in Young Adults: A Systematic Review and Meta-Analysis of RCTs.

Nutrients

Poor eating habits are common during young adulthood and influence chronic disease morbidity. This systematic review evaluates the effectiveness of interventions aiming to improve dietary intake among young adults and, identifies which behaviour change techniq…

Systematic review / meta-analysis 2018
Cancer and oncology

High ligation of the inferior mesenteric artery during sigmoid colon and rectal cancer surgery increases the risk of anastomotic leakage: a meta-analysis.

World journal of surgical oncology

Background The ideal level of ligation of the inferior mesenteric artery (IMA) during curative resection of sigmoid colon and rectal cancer is still controversial. The aim of this meta-analysis was to examine the impact of high ligation and low ligation of the…

Systematic review / meta-analysis 2020
Cancer and oncology

Immune Checkpoint Inhibitors and Immune-Related Adverse Events in Patients With Advanced Melanoma: A Systematic Review and Network Meta-analysis.

JAMA network open

Importance Since 2011, immune checkpoint inhibitors (ICIs) have been effective treatment options for advanced melanoma. Little is known about how risks of immune-related adverse events (irAEs) vary by ICIs. Objective To compare the risk of irAEs across differe…

Systematic review / meta-analysis 2018
Children's health

Vaccines for preventing typhoid fever.

The Cochrane database of systematic reviews

Background Typhoid fever and paratyphoid fever continue to be important causes of illness and death, particularly among children and adolescents in south-central and southeast Asia. Two typhoid vaccines are widely available, Ty21a (oral) and Vi polysaccharide …

Systematic review / meta-analysis 2019
Heart and blood vessels

Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis.

BMC medicine

Background Statins may prevent recurrent ischemic events after ischemic stroke. Determining which statin to use remains controversial. We aimed to summarize the evidence for the use of statins in secondary prevention for patients with ischemic stroke by compar…

Systematic review / meta-analysis 2021
Prevention and public health

Intention to COVID-19 vaccination and associated factors among health care workers: A systematic review and meta-analysis of cross-sectional studies.

American journal of infection control

Objectives To gain insight into willingness and its influencing factors to vaccinate against COVID-19 among health care workers (HCWs), and provide a scientific basis for more reasonable epidemic prevention and control strategies. Methods A comprehensive liter…