Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.
American journal of medical genetics. Part A
Achondroplasia is a genetic disorder that results in disproportionate short stature. The true prevalence of achondroplasia is unknown as estimates vary widely. This systematic literature review and meta-analysis was conducted to better estimate worldwide achon…
Dysphagia
Dysphagia is associated with increased risk of stroke-associated pneumonia (SAP). However, it is unclear what other factors contribute to that risk or which measures may reduce it. This systematic review aimed to provide evidence on interventions and care proc…
PloS one
A meta-analytic approach was used to identify potential risk factors for dry eye syndrome. PubMed, Embase, and the Cochrane library were systematically searched for studies investigated the risk factors for dry eye syndrome from their inception until September…
Clinical and translational gastroenterology
Objectives To summarize the literature on the influence of exercise on the gut microbiota of healthy adults. Methods A systematic and comprehensive search in electronic database, including SciELO, Scopus, PubMed, and Web of Science up to July 5, 2019. Eligibil…
PLoS medicine
Background Integration of HIV services with other health services has been proposed as an important strategy to boost the sustainability of the global HIV response. We conducted a systematic and comprehensive synthesis of the existing scientific evidence on th…
Pediatrics
Context Preterm brain injuries are common; neurodevelopmental outcomes following contemporary neonatal care are continually evolving. Objective To systematically review and meta-analyze neurodevelopmental outcomes among preterm infants after intraventricular h…
International journal of environmental research and public health
Background The present systematic review and meta-analysis investigated the cross-sectional and longitudinal associations between protein intake and sarcopenia in older adults. Methods Observational studies that investigated the association between protein int…
Postgraduate medical journal
Background Robotic-assisted total hip arthroplasty (THA) allows for accurate preoperative planning and component positioning, potentially enhancing implant survival and long-term outcomes. The relative efficacy and safety of robotic-assisted and conventional T…
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo
Objective This study aims to analyze the effects of social isolation on children's and teenagers' development, with emphasis on the possible impacts over their physical and mental health. Data source Review of the literature following the standards of PRISMA u…
Journal of medical Internet research
Background Chronic diseases contribute to high rates of disability and mortality. Patient engagement in chronic disease self-management is an essential component of chronic disease models of health care. Wearables provide patient-centered health data in real t…
Nutrients
Background The prevalence of type 2 diabetes is on the increase worldwide, and it represents about 90% of adults who are diagnosed with diabetes. Overweight and obesity, lifestyle, genetic predisposition and gut microbiota dysbiosis have been implicated as pos…
Journal of autism and developmental disorders
Group social skills interventions (GSSIs) are a commonly offered treatment for children with high functioning ASD. We critically evaluated GSSI randomised controlled trials for those aged 6-25 years. Our meta-analysis of outcomes emphasised internal validity, …
International journal for equity in health
Introduction It is well-established that low socioeconomic status (SES) influences one's health status, morbidity and mortality. Housing type has been used as an indicator of SES and social determinant of health in some studies. In Singapore, home ownership is…
PloS one
Objectives To perform a systematic review and network meta-analysis comparing stone-free rates following retrograde intrarenal surgery (RIRS), extracorporeal shock wave lithotripsy (SWL), and percutaneous nephrolithotomy (PCNL) treatments of renal stones. Mate…
Nutrients
Alongside an increase in obesity, society is experiencing the development of substantial technological advances. Interventions that are easily scalable, such as lifestyle (including diet and physical activity) mobile health (mHealth) self-monitoring, may be hi…
BMC geriatrics
Background A large number of studies have explored the association between frailty and mortality among COVID-19 patients, with inconsistent results. The aim of this meta-analysis was to synthesize the evidence on this issue. Methods Three databases, PubMed, Em…
Journal of orthopaedic surgery and research
Background This study aimed to evaluate the clinical efficacy of platelet-rich plasma (PRP) injection compared with hyaluronic acid (HA) injection for patients undergoing knee osteoarthritis. Methods We systematically searched electronic databases including Pu…
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Background Severe asthma is a major cause of morbidity. Some patients may benefit from biological therapies. Most evaluations of these treatments are derived from randomized controlled trials (RCTs), but few patients are eligible for these trials. Studies invo…
BMC medical education
Background Empathy allows a physician to understand the patient's situation and feelings and respond appropriately. Consequently, empathy gives rise to better diagnostics and clinical outcomes. This systematic review investigates the level of empathy among med…
PLoS medicine
Background Few studies have evaluated the association between preexisting vitamin D deficiency and incident tuberculosis (TB). We assessed the impact of baseline vitamins D levels on TB disease risk. Methods and findings We assessed the association between bas…
BMJ open
Introduction Medications cannot exert their effect if not taken as prescribed by patients. Our objective was to summarise the observational evidence on adherence to oral anticoagulants (OACs) among patients with atrial fibrillation (AF). Methods In March 2019,…
JAMA network open
Importance An increasing number of machine learning (ML)-based clinical decision support systems (CDSSs) are described in the medical literature, but this research focuses almost entirely on comparing CDSS directly with clinicians (human vs computer). Little i…
Journal of medical Internet research
Background Mobile ecological momentary assessment (mEMA) permits real-time capture of self-reported participant behaviors and perceptual experiences. Reporting of mEMA protocols and compliance has been identified as problematic within systematic reviews of chi…
Obesity reviews : an official journal of the International Association for the Study of Obesity
We aimed to assess the effectiveness of exercise training programs in adults with severe obesity undergoing bariatric surgery. A systematic search of controlled trials published up to October 2019 that assigned participants to either a preoperative or postoper…
