Open medical sources

Research library

Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

Research corpus

4,011+ records

Systematic review / meta-analysis 2020
Digestive system

Barriers and Facilitators That Influence Telemedicine-Based, Real-Time, Online Consultation at Patients' Homes: Systematic Literature Review.

Journal of medical Internet research

Background Health care providers are adopting information and communication technologies (ICTs) to enhance their services. Telemedicine is one of the services that rely heavily on ICTs to enable remote patients to communicate with health care professionals; in…

Peer-reviewed study 2017
Children's health

Economic and Health Predictors of National Postpartum Depression Prevalence: A Systematic Review, Meta-analysis, and Meta-Regression of 291 Studies from 56 Countries.

Frontiers in psychiatry

Background Postpartum depression (PPD) poses a major global public health challenge. PPD is the most common complication associated with childbirth and exerts harmful effects on children. Although hundreds of PPD studies have been published, we lack accurate g…

Systematic review / meta-analysis 2019
Prevention and public health

Global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2017, and forecasts to 2030, for 195 countries and territories: a systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017.

The lancet. HIV

Background Understanding the patterns of HIV/AIDS epidemics is crucial to tracking and monitoring the progress of prevention and control efforts in countries. We provide a comprehensive assessment of the levels and trends of HIV/AIDS incidence, prevalence, mor…

Systematic review / meta-analysis 2021
Prevention and public health

A systematic review of racial/ethnic and socioeconomic disparities in COVID-19.

International journal for equity in health

Background Preliminary evidence from the COVID-19 pandemic shows the presence of health disparities, especially in terms of morbidity and mortality. This study aimed to systematically review the evidence on the association of racial/ethnic and socioeconomic st…

Systematic review / meta-analysis 2019
Bones, joints and rehabilitation

How long does a hip replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up.

Lancet (London, England)

Background Total hip replacement is a common and highly effective operation. All hip replacements would eventually fail if in situ long enough and it is important that patients understand when this might happen. We aimed to answer the question: how long does a…

Systematic review / meta-analysis 2019
Prevention and public health

Consumer-Based Wearable Activity Trackers Increase Physical Activity Participation: Systematic Review and Meta-Analysis.

JMIR mHealth and uHealth

Background The range of benefits associated with regular physical activity participation is irrefutable. Despite the well-known benefits, physical inactivity remains one of the major contributing factors to ill-health throughout industrialized countries. Tradi…

Systematic review / meta-analysis 2020
Heart and blood vessels

Association of cardiovascular disease and 10 other pre-existing comorbidities with COVID-19 mortality: A systematic review and meta-analysis.

PloS one

Background Estimating the risk of pre-existing comorbidities on coronavirus disease 2019 (COVID-19) mortality may promote the importance of targeting populations at risk to improve survival. This systematic review and meta-analysis aimed to estimate the associ…

Systematic review / meta-analysis 2018
Cancer and oncology

Meta-analysis comparing upfront surgery with neoadjuvant treatment in patients with resectable or borderline resectable pancreatic cancer.

The British journal of surgery

Background Studies comparing upfront surgery with neoadjuvant treatment in pancreatic cancer may report only patients who underwent resection and so survival will be skewed. The aim of this study was to report survival by intention to treat in a comparison of …

Systematic review / meta-analysis 2020
Mental health

What are the barriers, facilitators and interventions targeting help-seeking behaviours for common mental health problems in adolescents? A systematic review.

BMC psychiatry

Background Increasing rates of mental health problems among adolescents are of concern. Teens who are most in need of mental health attention are reluctant to seek help. A better understanding of the help-seeking in this population is needed to overcome this g…

Systematic review / meta-analysis 2020
Women's health

Effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome: systematic review.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

Objective To evaluate the effect of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcome by performing a systematic review of available published literature on pregnancies affected by COVID-19. Methods We performed a systematic revie…

Systematic review / meta-analysis 2021
General medicine and research

Epidemiology of Traumatic Brain Injury in Europe: A Living Systematic Review.

Journal of neurotrauma

This systematic review provides a comprehensive, up-to-date summary of traumatic brain injury (TBI) epidemiology in Europe, describing incidence, mortality, age, and sex distribution, plus severity, mechanism of injury, and time trends. PubMed, CINAHL, EMBASE,…

Systematic review / meta-analysis 2019
Mental health

Prevalence of problematic smartphone usage and associated mental health outcomes amongst children and young people: a systematic review, meta-analysis and GRADE of the evidence.

BMC psychiatry

Background Over the past decade, smartphone use has become widespread amongst today's children and young people (CYP) which parallels increases in poor mental health in this group. Simultaneously, media concern abounds about the existence of 'smartphone addict…

Systematic review / meta-analysis 2018
Children's health

Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study.

The Lancet. Global health

Background The protozoan Cryptosporidium is a leading cause of diarrhoea morbidity and mortality in children younger than 5 years. However, the true global burden of Cryptosporidium infection in children younger than 5 years might have been underestimated in p…

Systematic review / meta-analysis 2020
Diabetes and metabolism

The Gut Microbiome, Aging, and Longevity: A Systematic Review.

Nutrients

Aging is determined by complex interactions among genetic and environmental factors. Increasing evidence suggests that the gut microbiome lies at the core of many age-associated changes, including immune system dysregulation and susceptibility to diseases. The…

Systematic review / meta-analysis 2021
Mental health

Measuring Subjective Sleep Quality: A Review.

International journal of environmental research and public health

Sleep quality is an important clinical construct since it is increasingly common for people to complain about poor sleep quality and its impact on daytime functioning. Moreover, poor sleep quality can be an important symptom of many sleep and medical disorders…

Systematic review / meta-analysis 2018
Diabetes and metabolism

Current guidelines for the management of non-alcoholic fatty liver disease: A systematic review with comparative analysis.

World journal of gastroenterology

The current epidemic of non-alcoholic fatty liver disease (NAFLD) is reshaping the field of hepatology all around the world. The widespread diffusion of metabolic risk factors such as obesity, type2-diabetes mellitus, and dyslipidemia has led to a worldwide di…

Systematic review / meta-analysis 2018
Mental health

Association of loneliness with all-cause mortality: A meta-analysis.

PloS one

Introduction Loneliness has social and health implications. The aim of this article is to evaluate the association of loneliness with all-cause mortality. Methods Pubmed, PsycINFO, CINAHL and Scopus databases were searched through June 2016 for published artic…