Open medical sources

Research library

Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

Research corpus

4,011+ records

Systematic review / meta-analysis 2021
Lungs and breathing

Estimation of the Prevalence of Progressive Fibrosing Interstitial Lung Diseases: Systematic Literature Review and Data from a Physician Survey.

Advances in therapy

Some patients with interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis exhibit a progressive clinical phenotype. These chronic progressive fibrosing ILDs have a variety of underlying diseases, and their prevalence is currently unknown. H…

Systematic review / meta-analysis 2020
Infections and immunity

Genetic variants of the human host influencing the coronavirus-associated phenotypes (SARS, MERS and COVID-19): rapid systematic review and field synopsis.

Human genomics

The COVID-19 pandemic has strengthened the interest in the biological mechanisms underlying the complex interplay between infectious agents and the human host. The spectrum of phenotypes associated with the SARS-CoV-2 infection, ranging from the absence of sym…

Systematic review / meta-analysis 2020
General medicine and research

Health Literacy in Surgery.

Health literacy research and practice

Background Low health literacy is associated with poor health outcomes in many chronic diseases and may have an important role in determining surgical outcomes. This study aims to comprehensively review the current state of science on adult health literacy in …

Systematic review / meta-analysis 2019
General medicine and research

Intralesional Injection of Botulinum Toxin Type A Compared with Intralesional Injection of Corticosteroid for the Treatment of Hypertrophic Scar and Keloid: A Systematic Review and Meta-Analysis.

Medical science monitor : international medical journal of experimental and clinical research

BACKGROUND The optimal treatment for hypertrophic scar and keloid remains controversial. Therefore, the aim of this systematic review and meta-analysis was to compare the effectiveness of intralesional injection of botulinum toxin type A compared with placebo …

Systematic review / meta-analysis 2022
Heart and blood vessels

Machine learning methods for functional recovery prediction and prognosis in post-stroke rehabilitation: a systematic review.

Journal of neuroengineering and rehabilitation

Background Rehabilitation medicine is facing a new development phase thanks to a recent wave of rigorous clinical trials aimed at improving the scientific evidence of protocols. This phenomenon, combined with new trends in personalised medical therapies, is ex…

Systematic review / meta-analysis 2018
Infections and immunity

Mosquito repellents for malaria prevention.

The Cochrane database of systematic reviews

Background Malaria is an important cause of illness and death across endemic regions. Considerable success against malaria has been achieved within the past decade mainly through long-lasting insecticide-treated nets (LLINs). However, elimination of the diseas…

Systematic review / meta-analysis 2018
Heart and blood vessels

Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies.

Arthritis research & therapy

Background Gout treatment remains suboptimal. Identifying populations at risk of developing gout may provide opportunities for prevention. Our aim was to assess the risk of incident gout associated with obesity, hypertension and diuretic use. Methods We conduc…

Systematic review / meta-analysis 2020
Heart and blood vessels

Plasma Biomarkers to Predict Cardiovascular Outcome in Patients With Peripheral Artery Disease: A Systematic Review and Meta-Analysis.

Arteriosclerosis, thrombosis, and vascular biology

Objective Patients with lower extremity peripheral artery disease (PAD) are at increased risk of major adverse cardiovascular events. Numerous plasma biomarkers have been investigated in lower extremity PAD, but none are used for clinical risk assessment. We a…

Systematic review / meta-analysis 2020
Mental health

Red and Processed Meat Consumption and Risk of Depression: A Systematic Review and Meta-Analysis.

International journal of environmental research and public health

Depression is one of the leading causes of disability worldwide, with more than 264 million people affected. On average, depression first appears during the late teens to mid-20s as result of a complex interaction of social, psychological and biological factor…

Systematic review / meta-analysis 2019
Women's health

The effectiveness of self-care and lifestyle interventions in primary dysmenorrhea: a systematic review and meta-analysis.

BMC complementary and alternative medicine

Background Menstrual pain is very common amongst young women. Despite the significant impact that menstrual pain has on academic attendance and performance, social activities and quality of life, most young women do not seek medical treatment but prefer to use…

Systematic review / meta-analysis 2022
General medicine and research

The Molecular Mechanisms of Action of Photobiomodulation Against Neurodegenerative Diseases: A Systematic Review.

Cellular and molecular neurobiology

Neurodegenerative diseases might be slow but relentless, as we continue to fail in treating or delaying their progression. Given the complexity in the pathogenesis of these diseases, a broad-acting approach like photobiomodulation can prove promising. Photobio…

Systematic review / meta-analysis 2021
Lungs and breathing

The role of CD8 + T lymphocytes in chronic obstructive pulmonary disease: a systematic review.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Objective and design This systematic review aims to establish the role of CD8 + T lymphocytes in COPD. Methods Forty-eight papers published in the last 15 years were identified for inclusion. Results CD8 + T-cells are increased in the lungs of patients with CO…