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Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

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4,011+ records

Systematic review / meta-analysis 2021
Children's health

Effects of therapeutic hypothermia on death among asphyxiated neonates with hypoxic-ischemic encephalopathy: A systematic review and meta-analysis of randomized control trials.

PloS one

Background Hypoxic perinatal brain injury is caused by lack of oxygen to baby's brain and can lead to death or permanent brain damage. However, the effectiveness of therapeutic hypothermia in birth asphyxiated infants with encephalopathy is uncertain. This sys…

Systematic review / meta-analysis 2021
Prevention and public health

Impact of Seasonality on Physical Activity: A Systematic Review.

International journal of environmental research and public health

Background The purpose of this study was to collect and analyze the available scientific evidence of the impact of seasonality on physical activity (PA). PA refers to walking, biking, sports and/or active recreation. Methods The search was performed in the fol…

Systematic review / meta-analysis 2020
Prevention and public health

Impact of the Built Environment and the Neighborhood in Promoting the Physical Activity and the Healthy Aging in Older People: An Umbrella Review.

International journal of environmental research and public health

(1) Background: The aim of this study is to establish which specific elements of the built environment can contribute to improving the physical activity of self-sufficient, noninstitutionalized and living in the city adults > 65 years. (2) Methods: An extensiv…

Systematic review / meta-analysis 2020
Bones, joints and rehabilitation

Interventions to improve adherence to anti-osteoporosis medications: an updated systematic review.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

An earlier systematic review on interventions to improve adherence and persistence was updated. Fifteen studies investigating the effectiveness of patient education, drug regimen, monitoring and supervision, and interdisciplinary collaboration as a single or m…

Systematic review / meta-analysis 2022
Cancer and oncology

Patient-Related Prognostic Factors for Anastomotic Leakage, Major Complications, and Short-Term Mortality Following Esophagectomy for Cancer: A Systematic Review and Meta-Analyses.

Annals of surgical oncology

Objective The aim of this study is to identify preoperative patient-related prognostic factors for anastomotic leakage, mortality, and major complications in patients undergoing oncological esophagectomy. Background Esophagectomy is a high-risk procedure with …

Systematic review / meta-analysis 2021
Children's health

Principles of Genomic Newborn Screening Programs: A Systematic Review.

JAMA network open

Importance Genomic newborn screening (gNBS) may optimize the health and well-being of children and families. Screening programs are required to be evidence based, acceptable, and beneficial. Objectives To identify what has been discovered following the reporti…

Systematic review / meta-analysis 2022
Diabetes and metabolism

Probiotics improve renal function, glucose, lipids, inflammation and oxidative stress in diabetic kidney disease: a systematic review and meta-analysis.

Renal failure

Aims The role of probiotics in the management of diabetic kidney disease (DKD) has been shown. Several current trials are investigating the effect of probiotics, which are widely used to modulate biomarkers of renal function, glucose, lipids, inflammation and …

Systematic review / meta-analysis 2022
Women's health

Progressive Resistance Training for Concomitant Increases in Muscle Strength and Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis.

Sports medicine (Auckland, N.Z.)

Background Older adults experience considerable muscle and bone loss that are closely interconnected. The efficacy of progressive resistance training programs to concurrently reverse/slow the age-related decline in muscle strength and bone mineral density (BMD…

Systematic review / meta-analysis 2021
Heart and blood vessels

Redefining β-blocker response in heart failure patients with sinus rhythm and atrial fibrillation: a machine learning cluster analysis.

Lancet (London, England)

Background Mortality remains unacceptably high in patients with heart failure and reduced left ventricular ejection fraction (LVEF) despite advances in therapeutics. We hypothesised that a novel artificial intelligence approach could better assess multiple and…

Systematic review / meta-analysis 2019
General medicine and research

The effectiveness of prescription drug monitoring programs at reducing opioid-related harms and consequences: a systematic review.

BMC health services research

Background In order to address the opioid crisis in North America, many regions have adopted preventative strategies, such as prescription drug monitoring programs (PDMPs). PDMPs aim to increase patient safety by certifying that opioids are prescribed in appro…

Systematic review / meta-analysis 2019
Infections and immunity

A systematic review and meta-analysis of community and primary-care-based hepatitis C testing and treatment services that employ direct acting antiviral drug treatments.

BMC health services research

Background Direct Acting Antiviral (DAAs) drugs have a much lower burden of treatment and monitoring requirements than regimens containing interferon and ribavirin, and a much higher efficacy in treating hepatitis C (HCV). These characteristics mean that initi…

Systematic review / meta-analysis 2018
Prevention and public health

A Systematic Review of Access to General Healthcare Services for People with Disabilities in Low and Middle Income Countries.

International journal of environmental research and public health

Background : A systematic review was undertaken to explore access to general healthcare services for people with disabilities in low and middle-income countries (LMICs). Methods : Six electronic databases were searched in February 2017. Studies comparing acces…

Systematic review / meta-analysis 2018
Women's health

Assessment of performance of the Gail model for predicting breast cancer risk: a systematic review and meta-analysis with trial sequential analysis.

Breast cancer research : BCR

Background The Gail model has been widely used and validated with conflicting results. The current study aims to evaluate the performance of different versions of the Gail model by means of systematic review and meta-analysis with trial sequential analysis (TS…

Systematic review / meta-analysis 2019
Diabetes and metabolism

Comparative Efficacy and Safety of Metformin, Glyburide, and Insulin in Treating Gestational Diabetes Mellitus: A Meta-Analysis.

Journal of diabetes research

To compare the efficacy and safety of metformin, glyburide, and insulin in treating gestational diabetes mellitus (GDM), a meta-analysis of randomized controlled trials (RCTs) was conducted. PubMed, Embase, CINAHL, Web of Science, and Cochrane Library to Novem…

Systematic review / meta-analysis 2022
Infections and immunity

Digital Health Technologies to Improve Medication Adherence and Treatment Outcomes in Patients With Tuberculosis: Systematic Review of Randomized Controlled Trials.

Journal of medical Internet research

Background Nonadherence to medication in tuberculosis (TB) hampers optimal treatment outcomes. Digital health technology (DHT) seems to be a promising approach to managing problems of nonadherence to medication and improving treatment outcomes. Objective This …