Open medical sources

Research library

Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

Research corpus

4,011+ records

Systematic review / meta-analysis 2020
Women's health

Risk of gestational diabetes mellitus in women achieving singleton pregnancy spontaneously or after ART: a systematic review and meta-analysis.

Human reproduction update

Background Women who achieve pregnancy by ART show an increased risk of obstetric and perinatal complications compared with those with spontaneous conception (SC). Objective and rationale The purpose of this systematic review and meta-analysis was to synthesiz…

Systematic review / meta-analysis 2018
Cancer and oncology

A Systematic Review of the Efficacy and Safety of Fecal Microbiota Transplant for Clostridium difficile Infection in Immunocompromised Patients.

Canadian journal of gastroenterology & hepatology

Background Fecal microbiota transplantation (FMT) has been shown to be effective in recurrent Clostridium difficile (CD) infection, with resolution in 80% to 90% of patients. However, immunosuppressed patients were often excluded from FMT trials, so safety and…

Systematic review / meta-analysis 2021
Cancer and oncology

Computed tomography-defined low skeletal muscle index and density in cancer patients: observations from a systematic review.

Journal of cachexia, sarcopenia and muscle

Background Computed tomography (CT) analysis of body composition has garnered interest as a potential prognostic tool in those with cancer. A range of pre-defined thresholds currently exist within the literature to define low skeletal muscle mass and density. …

Systematic review / meta-analysis 2019
Children's health

Effect of High-Intensity Interval Training versus Moderate-Intensity Continuous Training on Cardiorespiratory Fitness in Children and Adolescents: A Meta-Analysis.

International journal of environmental research and public health

Enhancing cardiorespiratory fitness (CRF) can lead to substantial health benefits. Comparisons between high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on CRF for children and adolescents are inconsistent and inconclusi…

Systematic review / meta-analysis 2018
Diabetes and metabolism

Effects of Newer Antidiabetic Drugs on Endothelial Function and Arterial Stiffness: A Systematic Review and Meta-Analysis.

Journal of diabetes research

Background Newer antidiabetic drugs, i.e., dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT-2) inhibitors, and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may exert distinct cardiovascular effects. We sought to explore …

Systematic review / meta-analysis 2021
Infections and immunity

Efficacy of alternative or adjunctive measures to conventional non-surgical and surgical treatment of peri-implant mucositis and peri-implantitis: a systematic review and meta-analysis.

International journal of implant dentistry

Purpose To evaluate the efficacy of alternative or adjunctive measures to conventional non-surgical or surgical treatment of peri-implant mucositis and peri-implantitis. Material and methods Prospective randomized and nonrandomized controlled studies comparing…

Systematic review / meta-analysis 2021
Mental health

Health Inequities in LGBT People and Nursing Interventions to Reduce Them: A Systematic Review.

International journal of environmental research and public health

Background Lesbian, gay, bisexual, and transgender (LGBT) people present poorer mental and physical health results compared to the heterosexual and cisgender population. There are barriers in the healthcare system that increase these health inequities. Objecti…

Systematic review / meta-analysis 2021
Children's health

Impact of breastfeeding interventions among United States minority women on breastfeeding outcomes: a systematic review.

International journal for equity in health

Background In the U.S., strong ethnic/racial, socioeconomic, demographic, and geographic breastfeeding (BF) inequities persist, and African American and Hispanic women are less likely to meet their breastfeeding goals compared to White women. This systematic r…

Systematic review / meta-analysis 2018
Heart and blood vessels

Selective serotonin reuptake inhibitor use during early pregnancy and congenital malformations: a systematic review and meta-analysis of cohort studies of more than 9 million births.

BMC medicine

Background In 2005, the FDA cautioned that exposure to paroxetine, a selective serotonin reuptake inhibitor (SSRI), during the first trimester of pregnancy may increase the risk of cardiac malformations. Since then, the association between maternal use of SSRI…

Systematic review / meta-analysis 2019
Prevention and public health

Comparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV-related disease in females and males.

The Cochrane database of systematic reviews

Background Uptake of human papillomavirus (HPV) vaccine remains low in many countries, although the bivalent and quadrivalent HPV vaccines given as a three-dose schedule are effective in the prevention of precancerous lesions of the cervix in women. Simpler im…

Systematic review / meta-analysis 2021
Prevention and public health

Demographic, regional and temporal trends of hyperuricemia epidemics in mainland China from 2000 to 2019: a systematic review and meta-analysis.

Global health action

Background Hyperuricemia (HUA) is becoming a global public health problem and associated with multiple diseases. Objective We conducted a systematic review to synthesize the pooled prevalence of HUA in mainland China and delineate its demographic, regional, an…

Systematic review / meta-analysis 2022
Diabetes and metabolism

Hospice care access inequalities: a systematic review and narrative synthesis.

BMJ supportive & palliative care

Background Inequalities in access to hospice care is a source of considerable concern; white, middle-class, middle-aged patients with cancer have traditionally been over-represented in hospice populations. Objective To identify from the literature the demograp…

Systematic review / meta-analysis 2021
Prevention and public health

Maternal Vitamin B12 Status During Pregnancy and Its Association With Outcomes of Pregnancy and Health of the Offspring: A Systematic Review and Implications for Policy in India.

Frontiers in endocrinology

Background Vitamins B12 and folate participate in the one-carbon metabolism cycle and hence regulate fetal growth. Though vitamin B12 deficiency is widely prevalent, the current public health policy in India is to supplement only iron and folic acid for the pr…