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Search more than 4,000 verified Europe PMC records and read the original English title, abstract, authors, journal and identifiers.

Research corpus

4,011+ records

Systematic review / meta-analysis 2023
Prevention and public health

The incidence rate of tuberculosis and its associated factors among HIV-positive persons in Sub-Saharan Africa: a systematic review and meta-analysis.

BMC infectious diseases

Background Tuberculosis, along with HIV, is the leading cause of mortality and morbidity globally. Despite the fact that several primary studies have been conducted on the incidence rate of tuberculosis in HIV-infected people in Sub-Saharan Africa, the regiona…

Systematic review / meta-analysis 2023
Lungs and breathing

Catheter-directed thrombolysis compared with systemic thrombolysis and anticoagulation in patients with intermediate- or high-risk pulmonary embolism: systematic review and network meta-analysis.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

Background Therapeutic options for intermediate- or high-risk pulmonary embolism (PE) include anticoagulation, systemic thrombolysis and catheter-directed thrombolysis (CDT); however, the role of CDT remains controversial. We sought to compare the efficacy and…

Systematic review / meta-analysis 2023
Infections and immunity

Complications of Unilateral Biportal Endoscopic Spinal Surgery for Lumbar Spinal Stenosis: A Systematic Review of the Literature and Meta-analysis of Single-arm Studies.

Orthopaedic surgery

Purpose This article aims to summarize the incidence of these complications through a meta-analysis, analyze the causes of complications and provide clinical promotion and recommendations. Methods Databases and retrieval platform including PubMed, Web of scien…

Systematic review / meta-analysis 2023
Prevention and public health

Economic evaluation of COVID-19 vaccination: A systematic review.

Journal of global health

Background Safe and effective vaccination is considered to be the most critical strategy to fight coronavirus disease 2019 (COVID-19), leading to individual and herd immunity protection. We aimed to systematically review the economic evaluation of COVID-19 vac…

Systematic review / meta-analysis 2023
Cancer and oncology

External radiotherapy combined with sorafenib has better efficacy in unresectable hepatocellular carcinoma: a systematic review and meta-analysis.

Clinical and experimental medicine

Advanced hepatocellular carcinoma (HCC) has a very low resectable rate. This meta-analysis aimed to compare efficacy of three combination strategies in treatment of advanced unresectable HCC with a view of guiding future selection of the best combination thera…

Systematic review / meta-analysis 2023
Diabetes and metabolism

Glucagon-like peptide 1 (GLP-1) receptor agonists in experimental Alzheimer's disease models: a systematic review and meta-analysis of preclinical studies.

Frontiers in pharmacology

Alzheimer's disease (AD) is a degenerative disease of the nervous system. Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), a drug used to treat type 2 diabetes, have been shown to have neuroprotective effects. This systematic review and meta-analysis eva…

Systematic review / meta-analysis 2025
Prevention and public health

Loneliness, social isolation, and living alone: a comprehensive systematic review, meta-analysis, and meta-regression of mortality risks in older adults.

Aging clinical and experimental research

Loneliness, social isolation, and living alone are significant risk factors for mortality, particularly in older adults. This systematic review and meta-analysis aimed to quantify their associations with all-cause and cause-specific mortality in older adults, …

Systematic review / meta-analysis 2024
General medicine and research

Long-Term Exposure to Particulate Matter and Mortality: An Update of the WHO Global Air Quality Guidelines Systematic Review and Meta-Analysis.

International journal of public health

Objectives For the development of the 2021 global air quality guidelines, the World Health Organization (WHO) commissioned a series of systematic reviews and meta-analyses to assess the association between exposure to air pollution and all-cause and cause-spec…

Systematic review / meta-analysis 2023
Bones, joints and rehabilitation

Minimal important change and difference for knee osteoarthritis outcome measurement tools after non-surgical interventions: a systematic review.

BMJ open

Objectives To systematically review and provide estimates of the minimal important change (MIC) and difference (MID) for outcome tools in people with knee osteoarthritis (OA) after non-surgical interventions. Design A systematic review. Data sources MEDLINE, C…

Systematic review / meta-analysis 2024
Prevention and public health

Rural-Urban Disparities in Colorectal Cancer Screening, Diagnosis, Treatment, and Survivorship Care: A Systematic Review and Meta-Analysis.

The oncologist

Background Rural residents have a higher prevalence of colorectal cancer (CRC) mortality compared to urban individuals. Policies have been aimed at improving access to CRC screening to reduce these outcomes. However, little attention has been paid to other det…

Systematic review / meta-analysis 2023
Diabetes and metabolism

The effects of probiotic and synbiotic supplementation on inflammation, oxidative stress, and circulating adiponectin and leptin concentration in subjects with prediabetes and type 2 diabetes mellitus: a GRADE-assessed systematic review, meta-analysis, and meta-regression of randomized clinical trials.

European journal of nutrition

Purpose Probiotics or synbiotics consumption have been suggested to reduce the risk of cardiovascular disease (CVD) through a decline in inflammation and oxidative stress, however, the results from studies are conflicting. This study filled this knowledge gap …

Systematic review / meta-analysis 2023
Women's health

The role of CD8+ T cells in endometriosis: a systematic review.

Frontiers in immunology

Background Endometriosis is a chronic disease affecting 6-10% of women of reproductive age. It is an important cause of infertility and chronic pelvic pain with poorly understood aetiology. CD8+ T (CD8 T) cells were shown to be linked to infertility and chroni…

Systematic review / meta-analysis 2023
General medicine and research

A Systematic Review of the Factors That Influence Teachers' Occupational Wellbeing.

International journal of environmental research and public health

Teachers belong to a high-demand occupational group and experience work-related challenges and discretely diverse emotional turmoils of varying intensity while teaching and interacting with students. These experiences often result in high stress levels that co…

Systematic review / meta-analysis 2023
General medicine and research

Correlation between the Altered Gut Microbiome and Lifestyle Interventions in Chronic Widespread Pain Patients: A Systematic Review.

Medicina (Kaunas, Lithuania)

Background : Lifestyle interventions have a direct impact on the gut microbiome, changing its composition and functioning. This opens an innovative way for new therapeutic opportunities for chronic widespread patients. Purpose : The goal of the present study w…